ALKP (Alkaline Phosphatase) Is found on the cell membranes (the outer borders) of liver cells and the bile duct. The ALKP in the blood will increase when bile is not flowing properly out of the liver.. My dog got 4 high things on a recent blood test. Total Protein 9.7 (Normal range 5.5-7.6) Albumin >6.0 (normal 2.5-4.0) GGT 160 (normal 0-14). The low specificity of serum total ALP is due to presence of several ALP isoenzymes (bone, liver, corticosteroid-induced) and the unique susceptibility of the enzyme to induction by drugs. Nodular hepatic hyperplasia is a common, age-related, incidental lesion in dogs with a reported incidence from 70% to 100% in dogs older than 14 years of age.

Elevated Alkaline Phosphatase in Dogs

Understanding High Alkaline Phosphatase Levels in Dogs Canine Liver Disease Resource Website

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What Causes High Alkaline Phosphatase In Dogs

What Causes High Alkaline Phosphatase Levels In Dogs

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High Alkaline Phosphatase in Dogs Increased ALKP in Dogs Causes and Treatment

High Alkaline Phosphatase in Dogs Increased ALKP in Dogs Causes and Treatment

Alkaline Phosphatase Levels Over 1000 In Dogs Canine Liver Disease Resource Website

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Elevated Alkaline Phosphatase in Dogs

What Causes High Alkaline Phosphatase In Dogs

Elevated Alkaline Phosphatase in Dogs

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Is an elevated ALP (alkaline phosphatase) level a sure sign of Cushing’s disease? Healthcare

Alkaline Phosphatase (ALP) Elevation Differential GrepMed

Elevated Alkaline Phosphatase in Dogs
An increase in ALP has a good sensitivity (86%), but a poor specificity (49-51%) for the diagnostic of hepatobiliary disease. The specificity of ALP for the diagnostic of hepatobiliary disease increases to 94% if combined with an increased serum GGT. 1. Considered significant if increase is 2-3x normal.. When alkaline phosphatase is increased in the bloodstream of a dog, the most common causes are liver disease, bone disease, or increased blood cortisol from specific drugs or because the animal has Cushing's disease (hyperadrenocorticism). In cats, the most common causes of increased alkaline phosphatase are liver and bone disease.